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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16557 | PNU-159682 | Topoisomerase | |
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin. | |||
T4677 | MMAD | Monomethylauristatin D,Demethyldolastatin 10,Monomethyl Dolastatin 10 | Microtubule Associated |
MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs). | |||
T40879 | 7-MAD-MDCPT | ||
7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs). | |||
T11116 | Duocarmycin MA | Others | |
Duocarmycin MA can be used against multi-drug resistant cell lines.Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. | |||
T10700 | (+)-CBI-CDPI1 | Others | |
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is a DNA alkylating agent and an antibody-drug conjugates (ADCs) toxin. | |||
T11117 | Duocarmycin MB | Others | |
Duocarmycin MB can be used against multi-drug resistant cell lines. Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. | |||
T40872 | 17-AEP-GA | ||
17-AEP-GA is a highly effective HSP90 antagonist compound that exhibits potent inhibition against the proliferation, survival, migration, and invasion of glioblastoma cells. Additionally, it demonstrates ADCs Toxin activ... | |||
T73948 | Duocarmycin DM | ||
Duocarmycin DM, a toxin for antibody-drug conjugates (ADCs), functions as a DNA minor-groove alkylator. It exerts its anticancer activity through a distinct curved indole structure combined with a spirocyclopropylcyclohe... | |||
T75117 | Py-MAA-Val-Cit-PAB-DX8951 | ||
Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1]. |